Lychnopholide
Lychnopholide is a sesquiterpene lactone derived from the Asteraceae, Lychnopholide exhibits anti-trypanosomal activity against Trypanosoma cruzi. lychnopholide encapsulated in nanocapsules reduces its toxicity to mammalian cells. Lychnopholide ameliorates Chagas disease in mouse models[1].
Product Specifications
CAS Number
[77448-64-7]
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lychnopholide.html
Smiles
C/C=C(C(O[C@@H](C[C@@]1(C)OC(/C(C)=C\2)=CC1=O)[C@]([H])([C@@]2(OC3=O)[H])C3=C)=O)\C
Molecular Formula
C20H22O6
Molecular Weight
358.39
References & Citations
[1]Milagre MM, et al., Lychnopholide loaded in surface modified polylactide nanocapsules (LYC-PLA-PEG-NC) cure mice infected by Trypanosoma cruzi strain a prototype of resistance to benznidazole and nifurtimox: First insights of its mechanism of action. Exp Parasitol. 2023 Dec;255:108647.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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