ATPIF1 Antibody (N-term) [APG02170G]
Product Specifications
Synonyms
ATPase inhibitor, mitochondrial, Inhibitor of F (1) F (o) -ATPase, IF (1), IF1, ATPIF1, ATPI
Gene Name
HGNC:871
Gene ID
93974
UniProt
Q9UII2
Chromosomal Location
Mitochondrion.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Endogenous F (1) F (o) -ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F (1) F (o) -ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F (1) F (o) -ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
Molecular Weight
12249
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATPIF1 Antibody (N-term) [APG02170G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=93974
Uniprot URL
https://www.uniprot.org/uniprot/Q9UII2
Available Sizes
Curated Selection
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