ATPIF1 Antibody (N-term) [APG02170G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATPIF1 Antibody (N-term) [APG02170G].

Synonyms

ATPase inhibitor, mitochondrial, Inhibitor of F (1) F (o) -ATPase, IF (1), IF1, ATPIF1, ATPI

Gene Name

HGNC:871

Gene ID

93974

UniProt

Q9UII2

Chromosomal Location

Mitochondrion.

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Endogenous F (1) F (o) -ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F (1) F (o) -ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F (1) F (o) -ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.