ELFN1 Antibody (C-term) [APR15811G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ELFN1 Antibody (C-term) [APR15811G].

Synonyms

Protein ELFN1, Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1, Protein phosphatase 1 regulatory subunit 28, ELFN1, PPP1R28

Gene Name

ELFN1

Gene ID

392617

UniProt

P0C7U0

Chromosomal Location

Membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Localizes to excitatory synapses onto somatostatin (Sst) -containing oriens-lacunosum moleculare (O-LM) interneurons

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity) . Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.