Vitexin

Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects[1][2].

Product Specifications

CAS Number

[3681-93-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy

Type

Natural Products

Related Pathways

Autophagy

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/vitexin.html

Concentration

10mM

Purity

99.90

Solubility

DMF : 4 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=CC=C(C2=CC(C(C(O)=CC(O)=C3[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)=C3O2)=O)C=C1

Molecular Formula

C21H20O10

Molecular Weight

432.38

Precautions

H302, H315, H319, H335

References & Citations

[1]He M, et al. A review on the pharmacological effects of vitexin and isovitexin. Fitoterapia. 2016 Dec;115:74-85.|[2] Lima LKF, et al. A Brief Review on the Neuroprotective Mechanisms of Vitexin. Biomed Res Int. 2018 Dec 5;2018:4785089.|[3]Jiang J, Dai J, Cui H. Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway. Biomed Pharmacother. 2018;99:583-590.