Ac-QPKK (Ac) -AMC
Ac-QPKK (Ac) -AMC is a fluorogenic substrate for sirtuin through sirtuin deacetylation[1].
Product Specifications
CAS Number
[1387005-23-3]
UNSPSC
12352209
Target
Sirtuin
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-qpkk-ac-amc.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CCCCNC(C)=O)NC([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@@H](NC(C)=O)CCC(N)=O)=O)=O)=O)=O)C=C1O3)=CC3=O
Molecular Formula
C36H52N8O9
Molecular Weight
740.85
References & Citations
[1]Galleano I, et al., A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation. J Med Chem. 2016 Feb 11;59 (3) :1021-31.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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