Ac-QPKK (Ac) -AMC

Ac-QPKK (Ac) -AMC is a fluorogenic substrate for sirtuin through sirtuin deacetylation[1].

Product Specifications

CAS Number

[1387005-23-3]

UNSPSC

12352209

Target

Sirtuin

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-qpkk-ac-amc.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=C(NC([C@H](CCCCNC(C)=O)NC([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@@H](NC(C)=O)CCC(N)=O)=O)=O)=O)=O)C=C1O3)=CC3=O

Molecular Formula

C36H52N8O9

Molecular Weight

740.85

References & Citations

[1]Galleano I, et al., A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation. J Med Chem. 2016 Feb 11;59 (3) :1021-31.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

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