ATG12 Antibody (N-term) [APR06983G]
Product Specifications
Background
Tissue Location: Ubiquitous..
Synonyms
Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12, APG12, APG12L
Gene Name
ATG12
Gene ID
9140
UniProt
O94817
Chromosomal Location
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12- ATG5 conjugate to the autolysosomal membrane
Applications
IF, IHC-P, WB
Dilution
WB--1:500 WB--1:2000 IF--1:200 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
Molecular Weight
15113
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATG12 Antibody (N-term) [APR06983G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9140
Uniprot URL
https://www.uniprot.org/uniprot/O94817
Available Sizes
Curated Selection
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