CLEC9A Antibody (Center) [APR15502G]
Product Specifications
Background
Tissue Location: In peripheral blood highly restricted on the surface of BDCA31 (+) dendritic cells and on a small subset of CD14 (+) and CD16 (-) monocytes.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLEC9A Antibody (Center) [APR15502G].
Synonyms
C-type lectin domain family 9 member A, CLEC9A
Gene Name
CLEC9A
Gene ID
283420
UniProt
Q6UXN8
Chromosomal Location
Membrane; Single- pass type II membrane protein
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Molecular Weight
27324
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=283420
Uniprot URL
https://www.uniprot.org/uniprot/Q6UXN8
Available Sizes
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