GPR84 Antibody (Center) [APR16623G]
Product Specifications
Background
Tissue Location: Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within the leukocyte population expression is higher in neutrophils and eosinophils relative to T- or B-lymphocytes
Synonyms
G-protein coupled receptor 84, Inflammation-related G-protein coupled receptor EX33, GPR84, EX33
Gene Name
GPR84
Gene ID
53831
UniProt
Q9NQS5
Chromosomal Location
Cell membrane; Multi-pass membrane protein.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G (i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
Molecular Weight
43705
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPR84 Antibody (Center) [APR16623G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=53831
Uniprot URL
https://www.uniprot.org/uniprot/Q9NQS5
Available Sizes
Curated Selection
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