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PFN2 Antibody (C-term) [AMM07111G]

Product Specifications

Background

Tissue Location: Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PFN2 Antibody (C-term) [AMM07111G].

Synonyms

Profilin-2, Profilin II, PFN2

Gene Name

PFN2

Gene ID

5217

UniProt

P35080

Chromosomal Location

Cytoplasm, cytoskeleton.

Applications

WB

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Molecular Weight

15046

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5217

Uniprot URL

https://www.uniprot.org/uniprot/P35080

Available Sizes

Frequently Asked Questions

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