M TLR4 Antibody (N-term) [APR10938G]
Product Specifications
Background
Tissue Location: Expressed in macrophages (at protein level) (PubMed:28098138) . Highly expressed in heart, spleen, lung and muscle Lower levels are found in liver and kidney (PubMed:23812099)
Synonyms
Toll-like receptor 4, CD284, Tlr4, Lps
Gene Name
Tlr4
Gene ID
21898
UniProt
Q9QUK6
Chromosomal Location
Cell membrane; Single-pass type I membrane protein. Early endosome {ECO:0000250|UniProtKB:O00206}. Cell projection, ruffle. Note=Upon complex formation with CD36 and TLR6, internalized through dynamin-dependent endocytosis Colocalizes with RFTN1 at cell membrane and then together with RFTN1 moves to endosomes, upon lipopolysaccharide stimulation {ECO:0000250|UniProtKB:O00206}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
985193099899762013349324380872
Molecular Weight
95519
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality M TLR4 Antibody (N-term) [APR10938G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=21898
Uniprot URL
https://www.uniprot.org/uniprot/Q9QUK6
Available Sizes
Curated Selection
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