M TLR4 Antibody (N-term) [APR10938G]

Product Specifications

Background

Tissue Location: Expressed in macrophages (at protein level) (PubMed:28098138) . Highly expressed in heart, spleen, lung and muscle Lower levels are found in liver and kidney (PubMed:23812099)

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality M TLR4 Antibody (N-term) [APR10938G].

Synonyms

Toll-like receptor 4, CD284, Tlr4, Lps

Gene Name

Tlr4

Gene ID

21898

UniProt

Q9QUK6

Chromosomal Location

Cell membrane; Single-pass type I membrane protein. Early endosome {ECO:0000250|UniProtKB:O00206}. Cell projection, ruffle. Note=Upon complex formation with CD36 and TLR6, internalized through dynamin-dependent endocytosis Colocalizes with RFTN1 at cell membrane and then together with RFTN1 moves to endosomes, upon lipopolysaccharide stimulation {ECO:0000250|UniProtKB:O00206}

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.