KCNA1 Antibody (Center) [AMM06077G]
Product Specifications
Background
Tissue Location: Detected adjacent to nodes of Ranvier in juxtaparanodal zones in spinal cord nerve fibers, but also in paranodal regions in some myelinated spinal cord axons (at protein level) (PubMed:11086297) . Detected in the islet of Langerhans (PubMed:21483673) .
Synonyms
Potassium voltage-gated channel subfamily A member 1, Voltage-gated K (+) channel HuKI, Voltage-gated potassium channel HBK1, Voltage-gated potassium channel subunit Kv11, KCNA1
Gene Name
KCNA1
Gene ID
3736
UniProt
Q09470
Chromosomal Location
Cell membrane; Multi-pass membrane protein. Membrane Cell projection, axon. Cytoplasmic vesicle. Perikaryon {ECO:0000250|UniProtKB:P10499}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P10499}. Cell projection, dendrite {ECO:0000250|UniProtKB:P16388}. Cell junction {ECO:0000250|UniProtKB:P16388}. Cell junction, synapse {ECO:0000250|UniProtKB:P16388}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250|UniProtKB:P10499}. Cell junction, synapse, presynapse {ECO:0000250|UniProtKB:P16388}. Note=Homotetrameric KCNA1 is primarily located in the endoplasmic reticulum. Interaction with KCNA2 and KCNAB2 or with KCNA4 and KCNAB2 promotes expression at the cell membrane (By similarity) . {ECO:0000250|UniProtKB:P10499, ECO:0000250|UniProtKB:P16388}
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
19903818171563681991277212077175171563681207717517156368199127721996895819307729199038181715636811026449171363962390336819307729
Molecular Weight
56466
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNA1 Antibody (Center) [AMM06077G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3736
Uniprot URL
https://www.uniprot.org/uniprot/Q09470
Available Sizes
Curated Selection
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