Mouse Clk4 Antibody (N-term) [APR17413G]

Product Specifications

Background

Tissue Location: Expressed in the hippocampus, the cerebellum and the olfactory bulb.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Clk4 Antibody (N-term) [APR17413G].

Synonyms

Dual specificity protein kinase CLK4, CDC-like kinase 4, Clk4

Gene Name

Clk4

Gene ID

12750

UniProt

O35493

Chromosomal Location

Nucleus.

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.