CHRM2 Antibody (Center) [AMM05767G]
Product Specifications
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHRM2 Antibody (Center) [AMM05767G].
Synonyms
Muscarinic acetylcholine receptor M2, CHRM2
Gene Name
CHRM2
Gene ID
1129
UniProt
P08172
Chromosomal Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein Note=Phosphorylation in response to agonist binding promotes receptor internalization. {ECO:0000250|UniProtKB:P06199}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3) ; this then triggers calcium ion release into the cytosol.
Molecular Weight
51715
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1129
Uniprot URL
https://www.uniprot.org/uniprot/P08172
Available Sizes
Curated Selection
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