AMIGO1 Antibody (C-term) [APR11395G]
Product Specifications
Synonyms
HGNC:20824
Gene Name
HGNC:20824
Gene ID
57463
UniProt
Q86WK6
Chromosomal Location
Cell membrane {ECO:0000250|UniProtKB:Q80ZD8}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q80ZD8} Perikaryon {ECO:0000250|UniProtKB:Q80ZD8}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q80ZD8}. Cell projection, axon {ECO:0000250|UniProtKB:Q80ZD7}. Note=Colocalizes with KCNB1 at high- density somatodendritic clusters on the surface of hippocampal and cortical neurons. Associated with axons of neuronal cells {ECO:0000250|UniProtKB:Q80ZD7, ECO:0000250|UniProtKB:Q80ZD8}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
Molecular Weight
55239
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMIGO1 Antibody (C-term) [APR11395G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=57463
Uniprot URL
https://www.uniprot.org/uniprot/Q86WK6
Available Sizes
Curated Selection
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