DOK7 Antibody (N-term) [AMM06947G]

Product Specifications

Background

Tissue Location: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOK7 Antibody (N-term) [AMM06947G].

Synonyms

Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25

Gene Name

DOK7

Gene ID

285489

UniProt

Q18PE1

Chromosomal Location

Cell membrane; Peripheral membrane protein. Cell junction, synapse Note=Accumulates at neuromuscular junctions.

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.