DOK7 Antibody (N-term) [AMM06947G]
Product Specifications
Background
Tissue Location: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level) .
Synonyms
Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25
Gene Name
DOK7
Gene ID
285489
UniProt
Q18PE1
Chromosomal Location
Cell membrane; Peripheral membrane protein. Cell junction, synapse Note=Accumulates at neuromuscular junctions.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
Molecular Weight
53097
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOK7 Antibody (N-term) [AMM06947G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=285489
Uniprot URL
https://www.uniprot.org/uniprot/Q18PE1
Available Sizes
Curated Selection
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