DHFRL1 Antibody (Center) [APR07559G]

Product Specifications

Background

Tissue Location: Expressed in numerous cell lines.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DHFRL1 Antibody (Center) [APR07559G].

Synonyms

Dihydrofolate reductase, mitochondrial, Dihydrofolate reductase-like protein 1, DHFRL1, DHFRP4

Gene Name

HGNC:27309

Gene ID

200895

UniProt

Q86XF0

Chromosomal Location

Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.