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Dab1 (Phospho Tyr220) rabbit pAb

Domain: The PID domain specifically binds to the Asn-Pro-Xaa-Tyr (P) motif found in many tyrosine-phosphorylated proteins. function: Adapter molecule functioning in neural development. May regulate SIAH1 activity. PTM: Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling. similarity: Contains 1 PID domain. subunit: Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.

Product Specifications

Background

Domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr (P) motif found in many tyrosine-phosphorylated proteins., function:Adapter molecule functioning in neural development. May regulate SIAH1 activity., PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity) . Also phosphorylated on Ser-524 independently of reelin signaling., similarity:Contains 1 PID domain., subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity) . Interacts with LRP1.

UniProt

O75553

Swiss Prot

O75553

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human Dab1 (Phospho Tyr220)

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight

60kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

60kD

Fragment

IgG

Other Product Names

Disabled homolog 1

Gene ID (Human)

1600

Available Sizes

Frequently Asked Questions

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