Dab1 (Phospho Tyr220) rabbit pAb
Domain: The PID domain specifically binds to the Asn-Pro-Xaa-Tyr (P) motif found in many tyrosine-phosphorylated proteins. function: Adapter molecule functioning in neural development. May regulate SIAH1 activity. PTM: Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling. similarity: Contains 1 PID domain. subunit: Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.
Product Specifications
Background
UniProt
O75553
Swiss Prot
O75553
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human Dab1 (Phospho Tyr220)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Other Product Names
Disabled homolog 1
Gene ID (Human)
1600
Available Sizes
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