DNAJC27 Antibody (N-term) [APR15783G]

Product Specifications

Background

Tissue Location: Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DNAJC27 Antibody (N-term) [APR15783G].

Synonyms

DnaJ homolog subfamily C member 27, Rab and DnaJ domain-containing protein, DNAJC27, RABJS, RBJ

Gene Name

DNAJC27

Gene ID

51277

UniProt

Q9NZQ0

Chromosomal Location

Nucleus {ECO:0000250|UniProtKB:Q8CFP6}.

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.