KCNJ13 Antibody (N-term) [AMM06103G]

Product Specifications

Background

Tissue Location: Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNJ13 Antibody (N-term) [AMM06103G].

Synonyms

Inward rectifier potassium channel 13, Inward rectifier K (+) channel Kir71, Potassium channel, inwardly rectifying subfamily J member 13, KCNJ13

Gene Name

KCNJ13

Gene ID

3769

UniProt

O60928

Chromosomal Location

Membrane; Multi-pass membrane protein.

Applications

WB, IHC-P

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.