KCNJ13 Antibody (N-term) [AMM06103G]
Product Specifications
Background
Tissue Location: Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord
Synonyms
Inward rectifier potassium channel 13, Inward rectifier K (+) channel Kir71, Potassium channel, inwardly rectifying subfamily J member 13, KCNJ13
Gene Name
KCNJ13
Gene ID
3769
UniProt
O60928
Chromosomal Location
Membrane; Multi-pass membrane protein.
Applications
WB, IHC-P
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.
Molecular Weight
40530
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNJ13 Antibody (N-term) [AMM06103G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3769
Uniprot URL
https://www.uniprot.org/uniprot/O60928
Available Sizes
Curated Selection
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