SFRS7 Antibody (N-term) [APR13286G]

Product Specifications

Background

Tissue Location: Brain, liver, kidney and lung.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SFRS7 Antibody (N-term) [APR13286G].

Synonyms

Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7

Gene Name

SRSF7

Gene ID

6432

UniProt

Q16629

Chromosomal Location

Nucleus. Cytoplasm

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1- NXT1 heterodimer for export (TAP/NXF1 pathway) ; enhances NXF1-NXT1 RNA- binding activity. RNA-binding is semi-sequence specific.