KCNJ4 Antibody (N-term) [AMM06129G]
Product Specifications
Background
Tissue Location: Heart, skeletal muscle, and several different brain regions including the hippocampus
Synonyms
Inward rectifier potassium channel 4, HIRK2, HRK1, Hippocampal inward rectifier, HIR, Inward rectifier K (+) channel Kir23, IRK-3, Potassium channel, inwardly rectifying subfamily J member 4, KCNJ4, IRK3
Gene Name
KCNJ4
Gene ID
3761
UniProt
P48050
Chromosomal Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Note=TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity) .
Molecular Weight
49500
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNJ4 Antibody (N-term) [AMM06129G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3761
Uniprot URL
https://www.uniprot.org/uniprot/P48050
Available Sizes
Curated Selection
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