MYO3B Antibody (C-term) [APR17507G]
Product Specifications
Background
Tissue Location: Expressed in retina, kidney and testis.
Synonyms
Myosin-IIIb, MYO3B
Gene Name
MYO3B
Gene ID
140469
UniProt
Q8WXR4
Chromosomal Location
Cytoplasm, cytoskeleton. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q1EG27}
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.
Molecular Weight
151829
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYO3B Antibody (C-term) [APR17507G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=140469
Uniprot URL
https://www.uniprot.org/uniprot/Q8WXR4
Available Sizes
Curated Selection
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