SHISA6 Antibody (N-term) [APR13308G]
Product Specifications
Background
Tissue Location: Expressed in the developing ventral mesencephalon.
Synonyms
Protein shisa-6 homolog, SHISA6
Gene Name
HGNC:34491
Gene ID
388336
UniProt
Q6ZSJ9
Chromosomal Location
Membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q3UH99}. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q3UH99}
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway.
Molecular Weight
55764
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SHISA6 Antibody (N-term) [APR13308G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=388336
Uniprot URL
https://www.uniprot.org/uniprot/Q6ZSJ9
Available Sizes
Curated Selection
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