RAB12 Antibody (N-term) [AMM07430G]
Product Specifications
Synonyms
Ras-related protein Rab-12, RAB12
Gene Name
RAB12
Gene ID
201475
UniProt
Q6IQ22
Chromosomal Location
Recycling endosome membrane {ECO:0000250|UniProtKB:P35283}; Lipid-anchor; Cytoplasmic side. Lysosome membrane {ECO:0000250|UniProtKB:P35283}; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane {ECO:0000250|UniProtKB:P51152}. Cytoplasmic vesicle, autophagosome {ECO:0000250|UniProtKB:P35283}
Applications
WB, FC
Dilution
FC--1:25 WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity) .
Molecular Weight
27248
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAB12 Antibody (N-term) [AMM07430G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=201475
Uniprot URL
https://www.uniprot.org/uniprot/Q6IQ22
Available Sizes
Curated Selection
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