ENT1 Antibody (C-term) [APR14290G]
Product Specifications
Background
Tissue Location: Detected in erythrocytes (at protein level) . Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.
Synonyms
Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1, SLC29A1, ENT1
Gene Name
SLC29A1
Gene ID
2030
UniProt
Q99808
Chromosomal Location
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells
Applications
WB, FC, IHC-P-Leica
Dilution
IHC-P-Leica--1:500 FC--1:25 WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter) . It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs) .
Molecular Weight
50219
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ENT1 Antibody (C-term) [APR14290G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2030
Uniprot URL
https://www.uniprot.org/uniprot/Q99808
Available Sizes
Curated Selection
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