ENT1 Antibody (C-term) [APR14290G]

Product Specifications

Background

Tissue Location: Detected in erythrocytes (at protein level) . Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ENT1 Antibody (C-term) [APR14290G].

Synonyms

Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1, SLC29A1, ENT1

Gene Name

SLC29A1

Gene ID

2030

UniProt

Q99808

Chromosomal Location

Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells

Applications

WB, FC, IHC-P-Leica

Dilution

IHC-P-Leica--1:500 FC--1:25 WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter) . It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs) .