GPD1L Antibody (N-term) [AMM05181G]

Product Specifications

Background

Tissue Location: Most highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPD1L Antibody (N-term) [AMM05181G].

Synonyms

Glycerol-3-phosphate dehydrogenase 1-like protein, GPD1-L, GPD1L, KIAA0089

Gene Name

HGNC:28956

Gene ID

23171

UniProt

Q8N335

Chromosomal Location

Cytoplasm. Note=Localized to the region of the plasma membrane

Applications

WB, IHC-P, FC

Dilution

WB--1:2000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3- phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD (H) balance induced by DPD1L.