CLDN7 Antibody (C-term) [APR15495G]

Product Specifications

Background

Tissue Location: Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLDN7 Antibody (C-term) [APR15495G].

Synonyms

Claudin-7, CLDN-7, CLDN7, CEPTRL2, CPETRL2

Gene Name

CLDN7

Gene ID

1366

UniProt

O95471

Chromosomal Location

Cell membrane; Multi-pass membrane protein. Basolateral cell membrane. Cell junction, tight junction. Note=Co-localizes with EPCAM at the basolateral cell membrane and tight junction

Applications

WB, IHC-P, FC

Dilution

WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.