What is the catalog number for MAPK7 Antibody (C-term) [APR14127G]?

The catalog number for MAPK7 Antibody (C-term) [APR14127G] is APR14127G.

What sizes are available for MAPK7 Antibody (C-term) [APR14127G]?

MAPK7 Antibody (C-term) [APR14127G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does MAPK7 Antibody (C-term) [APR14127G] come in?

MAPK7 Antibody (C-term) [APR14127G] is available in 4 different pack sizes.

Is MAPK7 Antibody (C-term) [APR14127G] in stock?

MAPK7 Antibody (C-term) [APR14127G] is currently made to order / not held in immediate stock. Contact us for lead time.

MAPK7 Antibody (C-term) [APR14127G]

Product Specifications

Background

Tissue Location: Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAPK7 Antibody (C-term) [APR14127G].

Synonyms

Mitogen-activated protein kinase 7, MAP kinase 7, MAPK 7, Big MAP kinase 1, BMK-1, Extracellular signal-regulated kinase 5, ERK-5, MAPK7, BMK1, ERK5, PRKM7

Gene Name

MAPK7

Gene ID

5598

UniProt

Q13164

Chromosomal Location

Cytoplasm. Nucleus. Nucleus, PML body. Note=Translocates to the nucleus upon activation

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Function

Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.