NOS3 Antibody (N-term) [APR08778G]
Product Specifications
Background
Tissue Location: Platelets, placenta, liver and kidney.
Synonyms
Nitric oxide synthase, endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, eNOS, NOS type III, NOSIII, NOS3
Gene Name
NOS3
Gene ID
4846
UniProt
P29474
Chromosomal Location
Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity
Applications
WB, IHC-P, IF, FC
Dilution
WB--1:1000 IHC-P--1:100~500 IF--1:10~50 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) -induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Molecular Weight
133275
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NOS3 Antibody (N-term) [APR08778G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4846
Uniprot URL
https://www.uniprot.org/uniprot/P29474
Available Sizes
Curated Selection
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