NURR1 (NR4A2) Antibody (N-term) [APR10842G]
Product Specifications
Background
Tissue Location: Expressed in a number of cell lines of T-cell, B- cell and fibroblast origin. Strong expression in brain tissue
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NURR1 (NR4A2) Antibody (N-term) [APR10842G].
Synonyms
Nuclear receptor subfamily 4 group A member 2, Immediate-early response protein NOT, Orphan nuclear receptor NURR1, Transcriptionally-inducible nuclear receptor, NR4A2, NOT, NURR1, TINUR
Gene Name
NR4A2
Gene ID
4929
UniProt
P43354
Chromosomal Location
Cytoplasm. Nucleus. Note=Mostly nuclear; oxidative stress promotes cytoplasmic localization
Applications
WB
Dilution
WB--1:1000 IHC-P--1:100~500 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity) .
Molecular Weight
66591
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4929
Uniprot URL
https://www.uniprot.org/uniprot/P43354
Available Sizes
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