BMPR1B Antibody (C-term) [AMM08566G]
Product Specifications
Synonyms
Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, CDw293, BMPR1B
Gene Name
BMPR1B
Gene ID
658
UniProt
O00238
Chromosomal Location
Cell membrane {ECO:0000250|UniProtKB:P36898}. Membrane; Single-pass type I membrane protein
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Molecular Weight
56930
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BMPR1B Antibody (C-term) [AMM08566G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=658
Uniprot URL
https://www.uniprot.org/uniprot/O00238
Available Sizes
Curated Selection
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