CALHM3 Antibody (N-term) [AMM08603G]
Product Specifications
Background
Tissue Location: Specifically expressed in circumvallate taste bud cells.
Synonyms
Calcium homeostasis modulator protein 3, Protein FAM26A, CALHM3, FAM26A
Gene Name
HGNC:23458
Gene ID
119395
UniProt
Q86XJ0
Chromosomal Location
Basolateral cell membrane {ECO:0000250|UniProtKB:J3QMI4}; Multi-pass membrane protein
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs) . CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Molecular Weight
38496
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CALHM3 Antibody (N-term) [AMM08603G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=119395
Uniprot URL
https://www.uniprot.org/uniprot/Q86XJ0
Available Sizes
Curated Selection
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