Cleaved LC3B Antibody [APR06991G]

Product Specifications

Background

Tissue Location: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cleaved LC3B Antibody [APR06991G].

Synonyms

Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B, Microtubule-associated protein 1 light chain 3 beta, MAP1LC3B, MAP1ALC3

Gene Name

HGNC:13352

Gene ID

81631

UniProt

Q9GZQ8

Chromosomal Location

Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes. LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329) . Localizes also to discrete punctae along the ciliary axoneme

Applications

IF, ICC

Dilution

IF--1:100 IF--1:10~50 ICC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.