DTX3 Antibody (N-term) [AMM08620G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DTX3 Antibody (N-term) [AMM08620G].

Synonyms

Probable E3 ubiquitin-protein ligase DTX3, 632-, Protein deltex-3, Deltex3, RING finger protein 154, DTX3, RNF154

Gene Name

DTX3

Gene ID

196403

UniProt

Q8N9I9

Chromosomal Location

Cytoplasm.

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity) . Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.