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SLC12A6 Antibody (N-term) [APR14251G]

Product Specifications

Background

Tissue Location: Highly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific. Expressed in the proximal tubule of the kidney (at protein level)

Synonyms

Solute carrier family 12 member 6, Electroneutral potassium-chloride cotransporter 3, K-Cl cotransporter 3, SLC12A6, KCC3

Gene Name

SLC12A6

Gene ID

9990

UniProt

Q9UHW9

Chromosomal Location

Basolateral cell membrane; Multi- pass membrane protein

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.

Molecular Weight

127617

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC12A6 Antibody (N-term) [APR14251G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=9990

Uniprot URL

https://www.uniprot.org/uniprot/Q9UHW9

Available Sizes

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