2'-Deoxyadenosine-15N5, d13
2'-Deoxyadenosine-15N5, d13 is deuterium and 15N labeled 2'-Deoxyadenosine. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer[2][3][4].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Caspase; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology; Metabolic Disease
Solubility
10 mM in DMSO
Smiles
[2H]C([15N]=C1[15N]([2H])[2H])=[15N]C2=C1[15N]=C([2H])[15N]2[C@@]3([2H])C([2H])([2H])[C@@](O[2H])([2H])[C@](C([2H])([2H])O[2H])([2H])O3
Molecular Formula
C10D13 15N5O3
Molecular Weight
269.29
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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