(2-pyridyldithio) -PEG1-hydrazine
(2-pyridyldithio) -PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[111625-28-6]
UNSPSC
12352203
Hazard Statement
H302, H312, H315, H317, H318, H332, H412
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-pyridyldithio-peg1-hydrazine.html
Purity
99.30
Solubility
10 mM in DMSO
Smiles
OCCSSC1=NC=CC=C1
Molecular Formula
C7H9NOS2
Molecular Weight
187.29
Precautions
H302, H312, H315, H317, H318, H332, H412
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Available Sizes
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