MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1802520-40-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-gly-gly-d-phe-gly-nh-ch2-o-ch2cooh.html
Purity
97.04
Solubility
10 mM in DMSO
Smiles
OC(COCNC(CNC([C@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O
Molecular Formula
C28H36N6O10
Molecular Weight
616.62
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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