Ent-Thiamphenicol
Ent-Thiamphenicol (ent-Dextrosulphenidol) is a enantiomer of Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[2].
Product Specifications
CAS Number
19934-71-5
Product Name Alternative
Ent-Thiophenicol; ent-Dextrosulphenidol
UNSPSC
12352005
Target
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ent-thiamphenicol.html
Smiles
O[C@H]([C@H](CO)NC(C(Cl)Cl)=O)C1=CC=C(S(C)(=O)=O)C=C1
Molecular Formula
C12H15Cl2NO5S
Molecular Weight
356.22
References & Citations
[1]A Marchese, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14 (6) :554-61.|[2]Marta Tikhomirov, et al. Pharmacokinetics of florfenicol and thiamphenicol in ducks. J Vet Pharmacol Ther. 2019 Jan;42 (1) :116-120.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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