MurA-IN-1
Product Specifications
UNSPSC Description
MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases)
Target Antigen
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mura-in-1.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1NC2=C(C=CC=C2)C3C1CC=C3)O
Molecular Weight
215.252
References & Citations
[1]Jeyanthy Eswaran, et al. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J. 2006 May 1;395(3):483-91.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141800/MurA-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141800/MurA-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
354815-90-0
Available Sizes
Curated Selection
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