4-Hydroxyacetophenone oxime

4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol) . Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent[1][2].

Product Specifications

CAS Number

[34523-34-7]

UNSPSC

12352005

Hazard Statement

H228, H302, H317, H319, H341, H351

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/4-hydroxyacetophenone-oxime.html

Purity

99.96

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C/C(C1=CC=C(O)C=C1)=N\O

Molecular Formula

C8H9NO2

Molecular Weight

151.16

Precautions

H228, H302, H317, H319, H341, H351

References & Citations

[1]Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22 (2) : p. 383-90.|[2]Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8 (6) :553-9.