8-Geranyloxypsoralen
8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1].
Product Specifications
CAS Number
7437-55-0
UNSPSC
12352005
Hazard Statement
H302, H317
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-geranyloxypsoralen.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=CC3=C(OC=C3)C(OC/C=C(C)/CC/C=C(C)/C)=C2O1
Molecular Formula
C21H22O4
Molecular Weight
338.40
Precautions
H302, H317
References & Citations
[1]Row EC, et al. Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4. Bioorg Med Chem. 2006 Jun 1;14 (11) :3865-71.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CYP3
Available Sizes
Frequently Asked Questions
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