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PI3K-IN-18 (dihydrochloride)

PI3K-IN-18 (Compound 1) dihydrochloride is a 4-morpholino-2-phenylquinazoline derivative and an inhibitor of PI3K p110α[1].

Product Specifications

CAS Number

[1188890-32-5]

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pi3k-in-18-dihydrochloride.html

Purity

99.70

Solubility

DMSO : 10 mg/mL (ultrasonic; warming)

Smiles

OC1=CC(C2=NC(N3CCOCC3)=C4SC=CC4=N2)=CC=C1.Cl.Cl

Molecular Formula

C16H17Cl2N3O2S

Molecular Weight

386.30

References & Citations

[1]Hayakawa M, et al. Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors. Bioorg Med Chem. 2006 Oct 15;14 (20) :6847-58.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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