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Anti-DPP10 Antibody

Rabbit Polyclonal Antibody specific to DPP10

Product Specifications

Product Name Alternative

Dipeptidyl peptidase IV-related protein 3, DPRP-3, Dipeptidyl peptidase X, DPP X, Dipeptidyl peptidase-like protein 2, DPL2

Gene Name

DPP10

NCBI Gene ID

<a href="https://www.ncbi.nlm.nih.gov/gene/?term=DPP10">DPP10</a>

UniProt

Q8N608

Cellular Locus

Cell membrane, Single-pass type II membrane protein

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to aa 521-539 of human DPP10.

Target Antigen

Inactive dipeptidyl peptidase 10

Target

DPP10

Clonality

Polyclonal

Type

Antibody

Applications

WB, ELISA

Field of Research

Neuroscience

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:15454437). Has no dipeptidyl aminopeptidase activity (PubMed:12662155). {PubMed:12662155, PubMed:15454437, PubMed:15671030}.

Additionnal Information

Immunoblotting: use at 1-5ug/mL. A band of approx. 75 kDa is detected, however protein oligermization may occur. <br><br>These are recommended concentrations. User should determine optimal concentrations for their applications.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Product Datasheet

https://www.qedbio.com/wp-content/uploads/pdf/28114.pdf

Specificity

This antibody recognizes human DPP10.

Formulation

PBS, pH 7.4.

Buffer pH

pH 7.4

Target Background

The DPP10 gene encodes a homolog of dipeptidyl peptidases that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases which includes DPP4, an enzyme that participates in chemokine processing.

CAS Number

9007-83-4

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