8-Epixanthatin
8-Epixanthatin is a potential colchicine binding site inhibitor isolated from Xanthium chinese Mill. 8-Epixanthatin can inhibit the activation of STAT3, induce apoptosis, and has anti-tumor activity[1].
Product Specifications
CAS Number
30890-35-8
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-epixanthatin.html
Purity
99.61
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C=C1[C@](CC=C2/C=C/C(C)=O)([H])[C@@](OC1=O)([H])C[C@@H]2C
Molecular Formula
C15H18O3
Molecular Weight
246.30
References & Citations
[1]Yu-Jin Lee, et al. 8-Epi-xanthatin induces the apoptosis of DU145 prostate carcinoma cells through signal transducer and activator of transcription 3 inhibition and reactive oxygen species generation. Phytother Res. 2021 Mar;35 (3) :1508-1520.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS753759-01 48 Well
Guinea pig Family with sequence similarity 160, member A1 ELISA Kit
Sign In for Pricing
View Details MBS753759-02 96 Well
Guinea pig Family with sequence similarity 160, member A1 ELISA Kit
Sign In for Pricing
View Details MBS753759-03 5x 96 Well
Guinea pig Family with sequence similarity 160, member A1 ELISA Kit
Sign In for Pricing
View Details MBS753759-04 10x 96 Well
Guinea pig Family with sequence similarity 160, member A1 ELISA Kit
Sign In for Pricing
View Details 
22551126 3x 1.0µg DNA
GPR27 CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details