8-Epixanthatin
8-Epixanthatin is a potential colchicine binding site inhibitor isolated from Xanthium chinese Mill. 8-Epixanthatin can inhibit the activation of STAT3, induce apoptosis, and has anti-tumor activity[1].
Product Specifications
CAS Number
30890-35-8
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-epixanthatin.html
Purity
99.61
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C=C1[C@](CC=C2/C=C/C(C)=O)([H])[C@@](OC1=O)([H])C[C@@H]2C
Molecular Formula
C15H18O3
Molecular Weight
246.30
References & Citations
[1]Yu-Jin Lee, et al. 8-Epi-xanthatin induces the apoptosis of DU145 prostate carcinoma cells through signal transducer and activator of transcription 3 inhibition and reactive oxygen species generation. Phytother Res. 2021 Mar;35 (3) :1508-1520.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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